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tecovirimat will increase the degree or influence of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Check. Tecovirimat is really a weak inhibitor of CYP2C8 and CYP2C19. Keep track of for adverse results if coadministered with sensitive substrates of such enzymes.Hyponatremia: Clinically significant hyponatremia (sodium three p